CAST
- CAST (company)
- CAST (gene)
- CAST (race)
- CAST tool
- CAST-128
- CAST-256
- CERN Axion Solar Telescope
- CRISPR-associated transposons
- Canadian Air-Sea Transportable Brigade Group
- Cardiac Arrhythmia Suppression Trial
- Carolina Actors Studio Theatre
- Cast (disambiguation)
- Centre for Analysis of Strategies and Technologies
- Certification Authorities Software Team
- Childhood Autism Spectrum Test
- China Academy of Space Technology
- China Association for Science and Technology
- Chronic addiction substitution treatment
- Coalition to Abolish Slavery and Trafficking
- College of Arts, Science and Technology
- Commercial Aviation Safety Team (CAST)
- Computer-adaptive sequential testing
- Computer-aided simple triage
- Curriculum Advice and Support Team