CAF
- CAF – Development Bank of Latin America
- CAFS (disambiguation)
- CANARIE
- CHAF1A
- Cactus Air Force
- Cafe (disambiguation)
- Caisse d'allocations familiales
- Calcium fluoride
- Calcium(I) fluoride
- Campaign for America's Future
- Canadian Arab Federation
- Canadian Armed Forces
- Cancer-associated fibroblast
- Cellular angiofibroma
- Central African Federation
- Central African Republic
- Centro Andaluz de la Fotografía
- Challenged Athletes Foundation
- Charities Aid Foundation
- Chief of Air Force (Australia)
- Club alpin français
- Coalition for App Fairness
- Coarray Fortran
- Commemorative Air Force
- Common Assessment Framework
- Community Adjustment Fund
- Conductive anodic filament
- Confederation of African Football
- Congressional Award Foundation
- Construcciones y Auxiliar de Ferrocarriles
- Continental Air Force
- Cooley's Anemia Foundation
- Core Audio Format
- Croatian Armed Forces
- Cyber Assessment Framework
- Pentapartito
- Qaf (disambiguation)
- Republic of China Air Force
- Royal Canadian Air Force
- SAP Composite Application Framework