William Brooke
William Brooke may refer to:
- William Brooke, 10th Baron Cobham, English peer and MP for Hythe and Rochester
- William Brooke (1565–1597), English MP for Rochester and Kent. Son of above. Killed in duel.
- William Brooke (MP, died 1643), English soldier and politician
- William Henry Brooke, English artist
- Willie Brooke, trade union administrator and politician
- Will Brooke, Chief of Staff to Senator Burns
- Will Brooke (businessman), Alabama businessman and political candidate