Bromocyclohexane
Bromocyclohexane is an organic compound with the chemical formula.
Uses and reactions
It is used to match the refractive index of PMMA for example in confocal microscopy of colloids. A mixture of cis-decalin and CXB can simultaneously match optical index and density of PMMA. Due to the moderate dielectric constant of CXB, PMMA acquires charges that can be screened by the addition of salt, leading to a very good approximation of colloidal hard sphere. A drawback is that CXB is a good solvent for PMMA, causing it to swell over time, which may lead to a poor determination of particle radii and determination of solid volume fraction.It is a standard coupling partner of cross [coupling reaction]s. Similarly, cyclohexyl bromide is a standard alkylating agent.
Stated applications in drug chemistry include the synthesis of gamfexine, drofenine, trihexyphenidyl, procyclidine, feclemine, hexocyclium, hexasonium, amedin & oxyphenonium respectively.