William Roe

• William Roe (civil servant), English customs official and auditor
• William F. Roe, Irish electrical engineer
• William Roe (priest), Anglican Archdeacon in Ireland
• William James Roe, American writer
• Bill Roe (cricketer), English cricketer
• Bill Roe (American football), American football linebacker
• Bill Roe (hurdler), American hurdler, 1965 All-American for the Washington Huskies track and field team
• Gordon Roe, English bishop
• Billy Roe, former Indy Racing League driver