William Chisholm
William Chisholm may refer to:
- William Chisholm (I), bishop of Dunblane
- William Chisholm (II), bishop of Dunblane and of Vaison, and nephew of William
- William Chisholm (Nova Scotia politician), Canadian politician who represented Antigonish, Nova Scotia
- William Chisholm (Upper Canada politician), Upper Canada politician and the founder of Oakville, Ontario
- William A. A. Chisholm, 1823 founder of the Woodville Republican newspaper in Woodville, Mississippi
- Bill Chisholm (businessman), American businessman
- Bill Chisholm (racewalker), American racewalker