BTK
- Bacillus thuringiensis kurstaki
- Baku–Tbilisi–Kars railway
- Batak languages
- Batik Air
- Bind, Torture, Kill
- Birth Through Knowledge
- Blood In, Blood Out (Exodus album)
- Born to Kill (disambiguation)
- Bratsk Airport
- Bruton's tyrosine kinase
- Btk-type zinc finger
- Bulgarian Telecommunications Company
- Church of Misery
- Dennis Rader
- Exodus (band)
- Information and Communication Technologies Authority
- Kaiser-Fleetwings XBTK
- Pillars of Truth
- Suffocation (album)
- Suicide Commando