BK-5-MAPBT


BK-5-MAPBT, also known as β-keto-5-MAPBT, is a possible entactogen of the benzothiophene and cathinone families. It is a potent monoamine releasing agent, including of serotonin and dopamine, and also acts as a potent serotonin 5-HT1B receptor agonist. Conversely, norepinephrine release was not reported. Unlike non-cathinone benzothiophenes like 5-MAPBT and 6-MAPBT, BK-5-MAPBT is very weak or inactive as a serotonin 5-HT2B receptor antagonist and monoamine oxidase A inhibitor. It produces anxiolytic-like and antiobsessional-like effects in the marble burying test in rodents. BK-5-MAPBT has been studied and patented by Matthew J. Baggott of Tactogen.