BD1060
BD1060 or N--1-pyrrolidineethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 3 ± 0.1 nM for the sigma-1 receptor and greater than 50 times selectivity over the sigma-2 receptor.
Like other sigma receptor antagonists, pretreating Swiss Webster mice with BD1060 significantly reduces the behavioral toxicity of cocaine.