Aziridination of Cyclic Nitrones Targeting Constrained Iminosugars
Aziridination of Cyclic Nitrones Targeting Constrained Iminosugars is a scholarly work by Alice Kanazawa and Sandrine Py, published in 2017 in ''Organic Letters''. The main subjects of the publication include combinatorial chemistry, reactivity, chemistry, cycloaddition, bicyclic compound, biological sequence, carbon–hydrogen bond activation, and stereochemistry. Rare C-7-substituted aziridinyl iminosugars can be synthesized through a short reaction sequence involving 1,3-cycloaddition of cyclic nitrones with alkynes and a Baldwin rearrangement of isoxazolines into bicyclic 2-acylaziridines.