Avrion Mitchison
Avrion Mitchison was a British zoologist and immunologist.
Biography
Mitchison was born in 1928, the son of the Labour politician Dick Mitchison and his wife, the writer Naomi (née Haldane). His uncle was the biologist J.B.S. Haldane and his grandfather the physiologist John Scott Haldane. His elder brothers are the bacteriologist Denis Mitchison and the zoologist Murdoch Mitchison.He was married to Lorna Margaret Martin, daughter of Maj-Gen John Simson Stuart Martin, CSI. They have five children, Tim, Matthew, Mary, Hannah and Ellen. Two are cell biologists Tim Mitchison and Hannah M. Mitchison.
He was educated at Leighton Park School and secured a Classics scholarship to Balliol College. He received his DPhil at New College, Oxford with Nobelist Sir Peter Medawar. This was followed by a long career as Professor of Zoology at University College London, where his uncle J.B.S. Haldane taught, at the National Institute of Medical Research at Mill Hill and as founding Director of the German Rheumatism Research Center Berlin in Germany. He was a Professor Emeritus at University College London.
Mitchison died on 28 December 2022, at the age of 94.
Mitchison's contributions to immunology include the discovery of both low dose and high dose tolerance for a single antigen, a surprising result in the context of basic clonal selection theory, but which can be understood in the context of immune network theory. He was also a founder member of the British Society for Immunology alongside John H. Humphrey, Bob White, and Robin Coombs.