The palace was constructed in 1898 on the orders of an Egyptian socialite, HannaSalehNissim. It was built as a gift for his wife, Anisa Wissa, and named after her.
The palace was constructed following an eclectic approach, combining Islamic and European architecture. The wood from France and Italy was used in the construction. Total area of the building is 4500 meters. The courtyard of the palace is decorated with Italian statues. The inside walls of the palace are ornamented, and the mirrors and marble fireplaces are heavily used in the palace.