Α,N,O-TMS

α,N,''O-Trimethylserotonin, also known as 5-methoxy-α,N''-dimethyltryptamine, is a psychedelic drug of the tryptamine and α-alkyltryptamine families. It is taken orally.

Use and effects

In his book TiHKAL, Shulgin lists the dose as 10 to 20mg orally and the duration as 6 to 8hours. The drug is significantly less potent than its non-N-methylated parent compound 5-MeO-AMT, which has a dose range of 2.5 to 4.5mg and a duration of 12 to 18hours.

Chemistry

Synthesis

The chemical synthesis of α,N,''O''-TMS has been described.

Analogues

Analogues of α,N,''O-TMS include α-methyltryptamine, α,N''-DMT, α,N,''N-TMT, α-methylserotonin, 5-MeO-AMT, and α,N'',N,''O''-TeMS, among others.