The southern terminus of SR 229 is located at Exit26 off I-85 south of Millstead. From Millstead, the route takes a northerly track to Tallassee. In Tallassee, the route briefly shares a concurrency with SR 14 whilst traveling in a northwesterly direction. Just to the south of Burlington, it splits from SR 14 and resumes a northerly track to Red Hill. At Red Hill, the route takes a turn to the west towards its northern terminus at SR 63.