Aglycone
| Chemical structures of digoxin and its aglycone digoxigenin |
An aglycone is the chemical compound remaining after the glycosyl group on a glycoside is replaced by a hydrogen atom. For example, the aglycone of a cardiac glycoside would be a steroid molecule.
Detection
A way to identify aglycone is proposed to extract it from Agave spp. by using H-NMR and Heteronuclear multiple bond correlation experiments. The HMBC experiment can be combined with other techniques such as mass spectrometry to further examine the structure and the function of aglycone.Samples of glycones and glycosides from limonoids can be simultaneously quantified through a high performance liquid chromatography method, where a binary solvent system and a diode array detector separate and detect them at a sensitivity of 0.25-0.50 μg.