Ageliferin


Ageliferin is a chemical compound produced by some sponges. It was first isolated from Caribbean and then Okinawan marine sponges in the genus Agelas. It often co-exists with the related compound sceptrin and other similar compounds. It has antibacterial properties and can cause biofilms to dissolve. Total syntheses have been independently accomplished by the research groups of Phil S. Baran at the Scripps [Research Institute], Chuo Chen at UT [Southwestern Medical Center], Patrick Harran at UCLA, and Daisuke Urabe at Toyama Prefectural University.