Adipokine
The adipokines, or adipocytokines are cytokines secreted by adipose tissue. Some contribute to an obesity-related low-grade state of inflammation or to the development of metabolic syndrome, a constellation of diseases including, but not limited to, type 2 diabetes, cardiovascular disease and atherosclerosis. The first adipokine to be discovered was leptin in 1994. Since that time, hundreds of adipokines have been discovered.
Members include:
- Leptin
- Adiponectin
- Apelin
- chemerin
- interleukin-6
- monocyte chemotactic protein-1
- plasminogen activator inhibitor-1
- retinol binding protein 4
- tumor necrosis factor
- visfatin
- omentin
- vaspin
- progranulin
- CTRP-4