ASC
- ASC (musician)
- ASC Pty Ltd
- ASC Shipbuilding
- ASC X12
- ASC X9
- ASK (disambiguation)
- Abstract simplicial complex
- Accounting Standards Codification
- Admiralty Sailing Craft
- Adorers of the Blood of Christ
- Advertising Standards Canada
- Aeronautical Systems Center
- Afrika-Studiecentrum Leiden
- After School Club
- Agence spatiale canadienne
- Agnes Scott College
- Airflow Sciences Corporation
- Al Ahly SC
- Alberta Securities Commission
- Alfred State College
- Alphabetical list of filename extensions (A–E)
- Altered state of consciousness
- Amalgamated Society of Core Makers of Great Britain and Ireland
- Ambulatory surgery center
- American National Standards Institute
- American Shakespeare Center
- American Signal Corporation
- American Society for Cybernetics
- American Society of Cinematographers
- American Society of Criminology
- American Society of Cytopathology
- American Solar Challenge
- American Song Contest
- American Southwest Conference
- American Specialty Cars
- Andres Soriano Colleges of Bislig
- Anglican Schools Commission
- Application Session Controller
- Aquaculture Stewardship Council
- Arnhem Space Centre
- Ashchurch for Tewkesbury railway station
- Asian Science Camp
- Asian Socialist Conference
- Assets Scrutiny Committee
- Association des Scouts du Canada
- Association of Speakers Clubs
- Asynchronous serial communication
- Australia Singapore Cable
- Australian Securities and Investments Commission
- Australian Singing Competition
- Australian Sports Commission
- Autism spectrum condition
- BMW R1200RT
- Indian Army Service Corps
- Key Code Qualifier
- PYCARD
- Pakistan Army
- Royal Army Service Corps
- TI Advanced Scientific Computer
- Taiwan Transportation Safety Board
- United States Army Sustainment Command