ARCT-021ARCT-021, also known as LUNAR-COV19, is a COVID-19 vaccine candidate developed by Arcturus Therapeutics.Medical usesIt requires the intramuscular injection with a single dose.PharmacologyARCT-021 is an self-amplifying mRNA vaccine.HistoryArcturus Therapeutics partnered with Singapore's Duke–NUS Medical School to develop a COVID-19 vaccine. The company also partnered with Catalent, a contract development and manufacturing organization, to manufacture multiple batches of Arcturus' COVID-19 mRNA vaccine candidate.Clinical trialsLUNAR-COV19 clinical trials in humans began in July 2020. On 4 January 2021, Arcturus Therapeutics started Phase-2 clinical trials.EconomicsArcturus has entered into development and supply agreements with the Economic Development Board of Singapore and supply agreements with the Israel Ministry of Health for LUNAR-COV19.