Ankyrin repeat domain 11Ankyrin repeat domain 11 is a protein that in humans is encoded by the ANKRD11 gene.FunctionThis locus encodes an ankyrin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome and Cornelia de Lange syndrome. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X.