ALX-1393

ALX-1393 is a glycine reuptake inhibitor.

Pharmacodynamics

ALX-1393 works by inhibiting the action of GLYT2. This causes elevated levels of glycine, an inhibitory neurotransmitter.

Potential uses

ALX-1393 has been shown to have potential as an analgesic. This is thought to be due to the elevated glycine levels reducing the transmission of the pain signals.
Tests have shown that it was able to help reduce cancer pain in a potent way.