AKAP8A-kinase anchor protein 8 is an enzyme that, in humans, is encoded by the AKAP8 gene.FunctionThe A-kinase anchor proteins are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A and confining it to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is redistributed to distinct locations during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.InteractionsAKAP8 has been demonstrated to interact with: Cyclin D3 DDX5, MCM2, MYCBP, and PRKAR2A.