5-Methoxypsilocybin


5-Methoxypsilocybin, also known as 5-MeO-psilocybin or as 5-methoxy-4-phosphoryloxy-N,''N''-dimethyltryptamine, is a compound of the tryptamine family which has been speculated may have psychedelic effects. It is related to psilocybin and 5-MeO-DMT and in terms of chemical structure and can be thought of as a combination of the structural features of the two compounds. 5-Methoxypsilocybin would be anticipated to possibly act as a prodrug of psilomethoxin similarly to how psilocybin acts as a prodrug of psilocin.
The Church of Sacred Synthesis claims that psilomethoxin is present in the 5-MeO-DMT-fed psilocybin mushrooms that they refer to as their sacrament and sell online. Along with psilomethoxin, 5-methoxypsilocybin may also be expected to be present in the mushrooms if their claims are true. However, a 2023 independent chemical analysis detected neither psilomethoxin nor 5-methoxypsilocybin in the church's mushrooms, but instead found the usual components of psilocybin mushrooms such as psilocybin, baeocystin, and psilocin.