5-MeO-NBnT
5-MeO-NBnT, also known as N-benzyl-5-methoxytryptamine or as 5-MeO-T-NB, is a serotonin receptor agonist of the tryptamine and 5-methoxytryptamine families related to 5-MeO-NMT.
Pharmacology
Pharmacodynamics
5-MeO-NBnT binds to the serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptors. It was assessed and found to be a potent partial agonist of the serotonin 5-HT2A receptor and full agonist of the serotonin 5-HT2C receptor. The drug was not evaluated in terms of effects in animals.
Chemistry
Synthesis
The chemical synthesis of 5-MeO-NBnT has been described.
Analogues
Analogues of 5-MeO-NBnT include N-benzyltryptamine, 4-HO-NBnT, 5-MeO-NBOMeT, and 5-MeO-NB3OMeT, among others. It is also analogous to N-benzylphenethylamines, for instance 25-NB, 25B-NB, and 25I-NBOMe.
History
5-MeO-NBnT was first described in the scientific literature by Keijiro Takagi and colleagues by 1969.