5-Ethoxy-DMT

5-Ethoxy-DMT, or 5-EtO-DMT, also known as 5-ethoxy-N,''N-dimethyltryptamine or as O''-ethylbufotenine, is a tryptamine derivative which has been previously synthesized as a chemical intermediate, but has not been studied to determine its pharmacology.

Chemistry

Analogues of 5-EtO-DMT include bufotenin, 5-MeO-DMT, 5-EtO-AMT, 5-AlO-AMT, 5-ethyl-DMT, 5-NOT, 5-BT, and 4-AcO-DMT, among others.
The widespread recreational use of 5-methoxytryptamines including 5-MeO-DMT, 5-MeO-MiPT and 5-MeO-DiPT has led to concern that the 5-ethoxy homologues of these drugs could emerge as novel designer drugs. Consequently, 5-EtO-DMT and other derivatives, including 5-EtO-DET, 5-EtO-DPT, 5-EtO-DiPT, 5-EtO-DALT, 5-EtO-MPT, 5-EtO-MiPT, 5-EtO-EiPT, 5-EtO-MET, and 5-EtO-EPT, have been synthesized as analytical standards in order to facilitate future research into these compounds.