4-HO-DsBT


4-HO-DsBT, also known as 4-hydroxy-N,''N-di-sec''-butyltryptamine, is a tryptamine derivative which acts as a serotonin receptor agonist.

Use and effects

4-HO-DsBT was first made by Alexander Shulgin and is mentioned in his book TiHKAL, but was never tested by him.

Interactions

Pharmacology

Pharmacodynamics

It has been tested in vitro and unlike the n-butyl and isobutyl isomers which are much weaker, the s-butyl derivative retains reasonable potency, with a similar 5-HT2A receptor affinity to MiPT but better selectivity over the 5-HT1A and 5-HT2B subtypes.

Chemistry

Analogues

s of 4-HO-DsBT include 4-HO-DBT, 4-HO-DiBT, 4-HO-DtBT, 4-HO-DiPT, 4-HO-McPeT, 4-HO-PiPT, 5-MeO-DBT, dibutyltryptamine, and N-''tert''-butyltryptamine, among others.

History

4-HO-DsBT was first described in the scientific literature by David Repke and colleagues by 1981.