4-Bromoresveratrol
4-Bromoresveratrol is an experimental drug which is a synthetic derivative of the natural product resveratrol, and has been investigated for anti-cancer properties. Unlike resveratrol itself which acts as a sirtuin activator, 4-bromoresveratrol acts as a selective inhibitor of the sirtuin enzymes SIRT1 and SIRT3. In animal models, it inhibits growth of melanomas and inhibited development of cancer stem cells in gastric cancer tissues.