4-AcO-DET
4-AcO-DET, also known as 4-acetoxy-N,''N''-diethyltryptamine as well as ethacetin or ethylacybin, is a psychedelic tryptamine. It was first synthesized in 1958 by Albert Hofmann in the Sandoz lab.Use and effects
4-AcO-DET is orally active, and doses of 10 to 25mg are common. Effects last 4 to 6hours. The free base is also active when smoked in a dose range of 5 to 20mg. Smoking 4-AcO-DET greatly speeds up the onset; peak effects are experienced within 10minutes, and are usually over within 1 hour.Interactions
Pharmacology
It is expected that 4-AcO-DET is quickly hydrolyzed into the free phenolic 4-HO-DET by serum esterases, but human studies concerning the metabolic fate of this drug are lacking.Chemistry
Analogues
s of 4-AcO-DET include diethyltryptamine, 4-HO-DET, ethocybin, 4-AcO-DMT, 4-AcO-DPT, 4-AcO-MET, and 4-AcO-MPT, among others.Society and culture
4-AcO-DET is not an explicitly nor implicitly controlled substance in Canada as of 2025.Finland
Listed in the "government decree on psychoactive substances banned from the consumer market".Sweden
health ministry Statens folkhälsoinstitut classified 4-AcO-DET as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-acetoxi-N,N-dietyltryptamin, making it illegal to sell or possess.4-AcO-DET is not an explicitly controlled substance in the United States. However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.