2C-B-3PIP-POMe
2C-B-3PIP-POMe is a serotonin receptor modulator of the phenethylamine, 2C, 3-phenylpiperidine, and NBOMe families. It is a cyclized phenethylamine and along with 2C-B-3PIP-NBOMe is an NBOMe derivative of 2C-B-3PIP. The drug is a mixture of cis- and trans- isomers. Its isomers show weak affinity for the serotonin 5-HT2A and 5-HT2C receptors, with these affinities being profoundly reduced relative to those of 2C-B. The cis isomer is a low-potency agonist of the serotonin 5-HT2A receptor, the serotonin 5-HT2B receptor, and the serotonin 5-HT2C receptor, whereas the trans isomer is inactive as an agonist of these receptors even at very high concentrations. The chemical synthesis of 2C-B-3PIP-POMe has been described. 2C-B-3PIP-POMe was first described in the scientific literature by Martin Hansen in 2010.