2025 Rolex Shanghai Masters – Singles
Qualifier Valentin Vacherot defeated his first cousin Arthur Rinderknech in the final, 4–6, 6–3, 6–3 to win the singles tennis title at the 2025 Shanghai Masters. It was his first career ATP Tour title, and he defeated five seeded opponents consecutively en route. Vacherot was the first Monégasque player to win a tour singles title, the first unseeded champion at the Shanghai Masters, and the lowest-ranked ATP Masters 1000 champion. Vacherot was the third qualifier to win a Masters 1000 title, and the fifth player overall to win a Masters 1000 as their first tour-level title.
For the first time in the tournament's history, two unseeded players contested the final, and this was only the third all-unseeded Masters 1000 final. Vacherot and Rinderknech are cousins, and were the first pair of family members to contest an ATP Tour final since brothers John and Patrick McEnroe at the 1991 Chicago Open.
At old, Novak Djokovic reached a record 80th Masters semifinal and extended his record as the oldest semifinalist. The second-round match between Djokovic and Marin Čilić was the oldest ATP 1000 singles match in terms of combined ages .
Jannik Sinner was the defending champion, but retired in the third round against Tallon Griekspoor.
Seeds
All seeds received a bye into the second round.Draw
Finals
Seeded players
The following are the seeded players. Seedings are based on ATP rankings as of 22 September 2025. Rankings and points before are as of 29 September 2025.| Seed | Rank | Player | Points before | Points dropping | Points won | Points after | Status | |||
| 1 | 1 |  nowrap|Withdrew due to ankle injuryWithdrawn seeded playersThe following players would have been seeded, but withdrew before the tournament began.
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