2024 US Open – Men's singles
Jannik Sinner defeated Taylor Fritz in the final, 6–3, 6–4, 7–5 to win the men's singles tennis title at the [2024 US Open (tennis)|US Open (tennis)|2024 US Open]. It was his second major title. Sinner was the fourth man to win both hardcourt singles majors in the same year, after Mats Wilander, Roger Federer and Novak Djokovic, and just the third man in the Open Era to win his first two major singles titles in the same year, joining Guillermo Vilas in 1977 and Jimmy Connors in 1974.
Djokovic was the defending champion, but lost in the third round to Alexei Popyrin. This marked Djokovic's earliest defeat at the US Open since 2006, and earliest defeat at any major since the 2017 Australian Open. It was the first year since 2017 that Djokovic did not win a major, the first year since 2002 that none of the Big Three won a major, and the first major since the 2004 French Open without any of the Big Three in the round of 16.
The semifinal between Fritz and Frances Tiafoe marked the first all-American major men's semifinal since Andre Agassi defeated Robby Ginepri at the 2005 US Open, with Fritz becoming the first American man to reach a major final since Andy Roddick at the 2009 Wimbledon Championships, and the first to do so at the US Open since Roddick in 2006.
This tournament marked the final major appearance of 2020 champion and former world No. 3 Dominic Thiem. He lost in the first round to Ben Shelton.
The first-round match between Dan Evans and Karen Khachanov was the longest match in the tournament's history at 5 hours and 35 minutes, surpassing the previous record of 5 hours and 26 minutes from the 1992 semifinal between Stefan Edberg and Michael Chang.
Seeded players
The following are the seeded players. Seedings are based on ATP rankings as of August 19, 2024. Rankings and points before are as of August 26, 2024.| Seed | Rank | Player | Points before | Points defending | Points won | Points after | Status |
| 1 | 1 |  Other entry informationWithdrawalsThe entry list was released based on the ATP rankings for the week of July 15, 2024.‡ – withdrew from entry list § – withdrew from main draw |