2023 San Luis Open Challenger

The 2023 San Luis Tennis Open was a professional tennis tournament played on outdoor clay courts. It was the 35th edition of the tournament for the men which is part of the 2023 ATP Challenger Tour and 1st edition for the women which is part of the 2023 WTA 125 tournaments. It took place at the Club Deportivo Potosino in San Luis Potosí, Mexico between 27 March and 9 April 2023.

Men's singles main-draw entrants

¹ Rankings are as of 20 March 2023.

The following players received wildcards into the singles main draw:

The following players received entry from the qualifying draw:

The following player received entry as a lucky loser:

¹ Rankings are as of 20 March 2023.

The following players received wildcards into the singles main draw:

The following players received entry from the qualifying draw:

The following pair received a wildcard into the doubles main draw:

;During the tournament

Tomás Barrios Vera def. Dominik Koepfer 7–6, 7–5.

Elisabetta Cocciaretto def. Sara Errani 5–7, 6–4, 7–5

Colin Sinclair / Adam Walton def. Benjamin Lock / Rubin Statham 5–7, 6–3, .

Aliona Bolsova / Andrea Gámiz def. Oksana Kalashnikova / Katarzyna Piter 7–6, 6–4