2023 Miami Open – Men's singles
Daniil Medvedev defeated Jannik Sinner in the final, 7–5, 6–3 to win the men's singles tennis title at the 2023 Miami Open. It was his fifth career Masters 1000 title, fourth title of 2023, and 19th career title overall. He became only the ninth man to win five Masters titles.
Carlos Alcaraz was the defending champion, but lost in the semifinals to Sinner in a rematch of their Indian Wells semifinal two weeks prior.
Novak Djokovic regained the ATP No. 1 ranking from Alcaraz at the end of the tournament, despite having been unable to enter the United States due to being unvaccinated for COVID-19.
Seeds
All seeds received a bye into the second round.Draw
Finals
Seeded players
The following are the seeded players. Seedings are based on ATP rankings as of March 20, 2023. Rankings and points before are as of March 20, 2023.| Seed | Rank | Player | Points before | Points defending | Points earned | Points after | Status | |||
| 1 | 1 |  Withdrawn playersThe following players would have been seeded, but withdrew before the tournament began.
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