2022 US Open – Mixed doubles
Storm Sanders and John Peers defeated Kirsten Flipkens and Édouard Roger-Vasselin in the final, 4–6, 6–4, to win the mixed doubles tennis title at the 2022 US Open.
Desirae Krawczyk and Joe Salisbury were the reigning champions, but Salisbury did not participate this year. Krawczyk partnered Neal Skupski, but lost in the second round to Caty McNally and William Blumberg.