2022 Italian Open – Women's doubles

Veronika Kudermetova and Anastasia Pavlyuchenkova defeated the defending champion Giuliana Olmos and her partner Gabriela Dabrowski in the final, 1–6, 6–4, to win the women's doubles tennis title at the 2022 Italian Open.
Sharon Fichman and Olmos were the reigning champions, but Fichman could not defend her title due to injury.

Seeded teams

The following are the seeded teams, based on WTA rankings as of April 25, 2022.

Country

Player

Country

Player

Rank¹

Seed

Australia

Other entry information

Protected ranking

Kaitlyn Christian / Han Xinyun

Alternates

Madison Brengle / Arina Rodionova

Withdrawals

;Before the tournament

Irina-Camelia Begu / Shelby Rogers → replaced by Nadiia Kichenok / Shelby Rogers
Lyudmyla Kichenok / Jeļena Ostapenko → replaced by Ekaterina Alexandrova / Anna Danilina
Nadiia Kichenok / Raluca Olaru → replaced by Kirsten Flipkens / Sara Sorribes Tormo
Veronika Kudermetova / Elise Mertens → replaced by Marta Kostyuk / Elena-Gabriela Ruse
Tereza Martincová / Aliaksandra Sasnovich → replaced by Madison Brengle / Arina Rodionova