2022 Iași Open

The 2022 Iași Open was a professional tennis tournament played on clay courts. It was the third edition of the men's tournament which was part of the 2022 ATP Challenger Tour and first edition of the women's tournament which was part of 2022 WTA 125 tournaments. It took place in Iași, Romania between 11 and 17 July 2022 for the men and between 1 and 7 August for the women.

Men's singles main-draw entrants

The following players received wildcards into the singles main draw:

The following players received entry into the singles main draw as alternates:

The following players received entry from the qualifying draw:

The following player received entry as lucky losers:

¹ Rankings as of 25 July 2022.

The following players received wildcards into the singles main draw:

The following players received entry from the qualifying draw:

The following players received entry as lucky losers:

;Before the tournament

† Rankings are as of 25 July 2022

The following pair received a wildcard entry into main draw:

The following pair received entry using a protected ranking:

;Before the tournament

Felipe Meligeni Alves def. Pablo Andújar 6–3, 4–6, 6–2.

Ana Bogdan def. Panna Udvardy 6–2, 3–6, 6–1

Geoffrey Blancaneaux / Renzo Olivo def. Diego Hidalgo / Cristian Rodríguez 6–4, 2–6, .

Darya Astakhova / Andreea Roșca def. Réka Luca Jani / Panna Udvardy 7–5, 5–7,