2022 Andalucía Challenger

The 2022 Andalucía Challenger was a professional clay court tennis tournament that took place from 28 March to 3 April 2022 at the Club de Tenis Puente Romano in Marbella, Spain. It was the fifth edition of the men's event and part of the 2022 ATP Challenger Tour. It was also the first edition of the women's event and a part of the 2022 WTA 125 calendar.

Men's singles main-draw entrants

¹ Rankings are as of 21 March 2022.

The following players received wildcards into the singles main draw:

Carlos Gimeno Valero
Dominic Thiem
Stan Wawrinka It was announced at the press conference that Stan Wawrinka, the former world number 3, would participate in ATP Challenger 125 in Puente Romano in Marbella. He achieved almost every possible milestone in professional tennis. Stan Wawrinka won three Grand Slam titles, 16 ATP titles and an Olympic gold in Beijing with Roger Federer in the men's doubles category.

The following players received entry into the singles main draw as alternates:

The following players received entry from the qualifying draw:

The following player received entry as a lucky loser:

¹ Rankings are as of 21 March 2022.

The following players received wildcards into the singles main draw:

The following players entered the main draw using a protected ranking:

;Before the tournament

The following pairs received wildcards into the doubles main draw:

Jaume Munar def. Pedro Cachin 6–2, 6–2.

Mayar Sherif def. Tamara Korpatsch 7–6, 6–4

Roman Jebavý / Philipp Oswald def. Hugo Nys / Jan Zieliński 7–6, 3–6, .

Irina Bara / Ekaterine Gorgodze def. Vivian Heisen / Katarzyna Kawa 6–4, 3–6,