2021 Murray River Open
The 2021 Murray River Open was a tournament on the 2021 ATP Tour. It was played on outdoor hard courts in Melbourne, Australia. It was organised as a lead-up tournament to the 2021 Australian Open, and was held at the same venue, due to other tournaments in Australia being cancelled as a result from the COVID-19 pandemic. This tournament took place simultaneously with the 2021 Great Ocean Road Open and the 2021 ATP Cup.
Points and prize money
Prize money
| Event | W | F | SF | QF | Round of 16 | Round of 32 | Round of 64 |
| Singles | $19,500 | $13,255 | $10,000 | $7,400 | $5,500 | $4,000 | $2,500 |
| Doubles* | $7,200 | $5,760 | $4,560 | $3,360 | $2,160 | $1,200 |
*per team
Singles main-draw entrants
Seeds
- 1 Rankings are as of January 25, 2021
Other entrants
The following players received wildcards into the main draw:The following players have been accepted directly into the main draw using a protected or a special ranking:
The following player received entry as an alternate:
Withdrawals
;Before the tournament- Alejandro Davidovich Fokina → replaced by Yūichi Sugita
- João Sousa → replaced by James Duckworth
- Bernard Tomic → replaced by Harry Bourchier
Retirements
Doubles main-draw entrants
Seeds
Other entrants
The following pairs received wildcards into the doubles main draw:The following pair received entry using a protected ranking: