2021–22 Super League Greece
The 2021–22 Super League Greece, known as Super League 1 Interwetten for sponsorship reasons, was the 86th season of the Super League Greece, the top Greek professional league for association football clubs, since its establishment in 1959. Olympiacos were the defending champions.
Teams
Fourteen teams competed in the league – the top twelve teams from the previous season, the play-off winner and one team promoted from Super League 2. The first club to be promoted was Ionikos, after beating Ergotelis 2–1 on 19 May 2021. Ionikos played in the Super League for the first time since the 2006–07 season. AEL were relegated to 2021–22 Super League Greece 2, ending their four-year stay in the top flight.| Promoted from 2020–21 Super League Greece 2 | Relegated from 2020–21 Super League Greece |
| Ionikos | AEL |
Play-off round
The top six teams from Regular season will meet twice for places in 2022–23 UEFA Champions League and 2022–23 UEFA Europa Conference League as well as deciding the league champion.Play-out round
Season statistics
Top scorers
| Rank | Player | Club | Goals | |||||||||||||||||||||||
| 1 |  Top assists
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