| Date | Round | Vrs | H/A | Venue | Result | Score | Tries | Goals | Att | Live on TV |
| 7/2/15 | 1 | Salford | H | Halliwell Jones Stadium | W | 22-8 | Myler, Higham, Atkins, R.Evans | Ratchford 3/4 | 11,864 | - |
| 13/2/15 | 2 | Hull F.C. | A | KC Stadium | W | 7-6 | Clark | O'Brien 1/1, O'Brien 1 DG | 12,000 | - |
| 28/2/15 | 3 | Catalans Dragons | A | Stade Gilbert Brutus | L | 18-38 | Monaghan, Wheeler, Philbin | O'Brien 3/3 | 8,946 | Sky Sports |
| 8/3/15 | 4 | Hull Kingston Rovers | H | Halliwell Jones Stadium | W | 32-24 | Russell, Monaghan, Philbin, Wheeler, Currie | Ratchford 4/6 | 9,587 | - |
| 13/3/15 | 5 | Leeds | H | Halliwell Jones Stadium | W | 18-6 | Penny, Ratchford, Atkins | Ratchford 3/3 | 10,075 | Sky Sports |
| 19/3/15 | 6 | St. Helens | A | Langtree Park | L | 24-32 | Clark, Higham, Penny, Hill | Ratchford 1/1, O'Brien 3/3 | 12,618 | Sky Sports |
| 27/3/15 | 7 | Huddersfield | H | Halliwell Jones Stadium | L | 10-29 | O'Brien, Penny | O'Brien 1/2 | 9,019 | - |
| 2/4/15 | 8 | Widnes | A | Halton Stadium | L | 10-30 | Westwood, Currie | O'Brien 1/2 | 7,768 | - |
| 6/4/15 | 9 | Castleford | H | Halliwell Jones Stadium | L | 14-22 | Ratchford, Atkins, Penny | O'Brien 1/3 | 8,518 | Sky Sports |
| 11/4/15 | 10 | Wakefield Trinity | H | Halliwell Jones Stadium | W | 80-0 | Ormsby, T.King, Clark, Myler, Sims, Ratchford, Westwood, Monaghan, Currie | Ratchford 12/14 | 8,036 | - |
| 16/4/15 | 11 | Wigan | A | DW Stadium | L | 20-30 | Monaghan, Bridge, Currie | Ratchford 2/4 | 14,175 | Sky Sports |
| 24/4/15 | 12 | Leeds | A | Headingley Stadium | W | 29-10 | Ormsby, Monaghan, Sims, Currie, Asotasi | Ratchford 4/5, Patton 1 DG | 17,430 | Sky Sports |
| 3/5/15 | 13 | Widnes | H | Halliwell Jones Stadium | W | 22-20 | Ormsby, Monaghan, Clark, Westwood | Ratchford 1/5 | 10,856 | - |
| 10/5/15 | 14 | Hull F.C. | H | Halliwell Jones Stadium | L | 26-27 | Monaghan, Currie, Ormsby | Ratchford 2/4, Bridge 1/1 | 9,697 | - |
| 22/5/15 | 15 | Salford | A | AJ Bell Stadium | W | 34-18 | Currie, Ormsby, Ratchford, Dwyer | Ratchford 5/6 | 6,159 | - |
| 31/5/15 | 16 | St. Helens | N | St James' Park | L | 16-20 | Ratchford, Harrison, Atkins | Bridge 2/3 | 26,970 | Sky Sports |
| 5/6/15 | 17 | Catalans Dragons | H | Halliwell Jones Stadium | W | 26-18 | Currie, Atkins, Hill | O'Brien 3/5 | 8,611 | Sky Sports |
| 14/6/15 | 18 | Huddersfield | A | Galpharm Stadium | L | 19-30 | Clark, O'Brien, Harrison | O'Brien 3/3, O'Brien 1 DG | 5,797 | - |
| 19/6/15 | 19 | Hull Kingston Rovers | A | Craven Park | L | 10-36 | Hill, Ormsby | Patton 1/2 | 7,455 | Sky Sports |
| 2/7/15 | 20 | Wigan | H | Halliwell Jones Stadium | W | 17-6 | Myler, Atkins, O'Brien | O'Brien 2/3, O'Brien 1 DG | 10,504 | Sky Sports |
| 12/7/15 | 21 | Wakefield Trinity | A | Belle Vue | W | 40-20 | Ratchford, Philbin, Russell, Westwood, Clark, Myler | O'Brien 6/7 | 3,354 | - |
| 16/7/15 | 22 | St. Helens | H | Halliwell Jones Stadium | L | 14-20 | Currie, Penny | O'Brien 3/3 | 11,618 | Sky Sports |
| 26/7/15 | 23 | Castleford | A | The Jungle | W | 44-6 | Monaghan, Westwood, O'Brien, Ormsby, Currie, Ratchford, Wilde, Myler | O'Brien 4/9 | 7,239 | - |
