2005 Wimbledon Championships – Mixed doubles

Wayne and Cara Black were the defending champions but lost in the second round to Mahesh Bhupathi and Mary Pierce.
Bhupathi and Pierce defeated Paul Hanley and Tatiana Perebiynis in the final, 6–4, 6–2 to win the mixed doubles tennis title at the 2005 Wimbledon Championships.

Seeds

All seeds received a bye into the second round.
Bob Bryan / Rennae Stubbs '
Wayne Black / Cara Black '
Jonas Björkman / Lisa Raymond '
Kevin Ullyett / Liezel Huber '
Mike Bryan / Martina Navratilova '
Todd Woodbridge / Samantha Stosur '
Leoš Friedl / Janette Husárová '
Mark Knowles / Venus Williams '
Pavel Vízner / Nicole Pratt '
Nenad Zimonjić / Katarina Srebotnik '
Jared Palmer / Corina Morariu '
Olivier Rochus / Kim Clijsters '
Julian Knowle / Anna-Lena Grönefeld '
Dominik Hrbatý / Elena Likhovtseva '
Martin Damm / Květa Peschke
Andy Ram / Conchita Martínez ''''