2004–05 Cuban National Series
The 44th Cuban National Series was won by Santiago de Cuba over Havana. Industriales, who had the best regular season record, were eliminated in the first round by Sancti Spíritus.
Regular season standings
Western zone
| Team | W | L | PCT. | GB |
| Industriales | 59 | 30 | .656 | - |
| Havana Province | 54 | 35 | .600 | 5 |
| Sancti Spíritus | 54 | 36 | .600 | 5½ |
| Cienfuegos | 31 | 59 | .344 | 28½ |
Eastern zone
| Team | W | L | PCT. | GB |
| Santiago de Cuba | 55 | 35 | .611 | - |
| Granma | 50 | 40 | .556 | 5 |
| Holguín | 37 | 53 | .411 | 18 |
| Guantánamo | 33 | 57 | .367 | 22 |