2-Methoxyamphetamine
2-Methoxyamphetamine, also known as ortho-methoxyamphetamine, is a drug of the amphetamine family. It is substantially weaker in inhibiting the reuptake of and inducing the release of the monoamine neurotransmitters compared to related agents such as amphetamine, MMA, and PMA, and may instead act as a β-adrenergic receptor agonist similarly to its N-methylated analogue methoxyphenamine. The drug also shows relatively weak affinity for serotonin receptors, including the serotonin 5-HT1 and 5-HT2 receptors. 2-MA fully substitutes for dextroamphetamine in rodent drug discrimination tests.