2-Hydroxysaclofen
2-Hydroxysaclofen is a GABAB receptor antagonist and an analogue of saclofen.
Pharmacodynamics
2-Hydroxysaclofen binds to the GABAB receptor, but this is selective for the -enantiomer, while the -enantiomer does not bind to the GABAB protein.2-Hydroxysaclofen has been reported to be more potent than saclofen.