1995 Cal Poly Mustangs football team

The 1995 Cal Poly Mustangs football team represented California Polytechnic State University, San Luis Obispo as a member of the American West Conference during the 1995 NCAA Division I-AA football season. Led by second-year head coach Andre Patterson, Cal Poly compiled an overall record of 5–6 with a mark of 2–1 in conference play, placing second in the AWC. The team outscored its opponents 411 to 271 for the season. The Mustangs played home games at Mustang Stadium in San Luis Obispo, California.