1981 African Cup of Champions Clubs
The African Cup of Champions Clubs 1981 was the 17th edition of the annual international club football competition held in the CAF region, the African Cup of Champions Clubs. It determined that years club champion of association football in Africa.
The tournament was played by 31 teams and was used a playoff scheme with home and away matches. JE Tizi Ouzou from Algeria won that final, and became for the first time CAF club champion.
Semi-finals
Top scorers
The top scorers from the 1981 African Cup of Champions Clubs are as follows:| Rank | Name | Team | Goals |
| 1 |  |1972NotificationJE Tizi Ouzou are now called JS Kabylie. |