1980–81 KNVB Cup

The 1980-81 KNVB Cup 63rd edition of the Dutch national football annual knockout tournament for the KNVB Cup. 46 teams contested, beginning on 6 September 1980 and ending at the final on 28 May 1981.
AZ from Alkmaar beat Ajax 3–1 and won the cup for the second time.
During the quarter and semi-finals, two-legged matches were held.

Teams

All 18 participants of the Eredivisie 1980-81
All 19 participants of the Eerste Divisie 1980-81
9 teams from lower leagues

First round

The matches of the first round were played on 6-7 September 1980.
₁ Eerste Divisie; _A Amateur teams

Second round

The matches of the second round were played on November 15 and 16, 1980. The Eredivisie clubs entered the tournament here.
_E Eredivisie

Round of 16

The matches of the round of 16 were played on January 24 and 25, 1981.

Quarter finals

The quarter finals were played on February 25 and April 1, 1980.

Semi-finals

The semi-finals were played on April 14 and May 12, 1980.

Final

AZ also won the Dutch Eredivisie championship, thereby taking the double. They would participate in the European Cup, so finalists Ajax could play in the Cup Winners' Cup.