| Season | Group 1 | Group 2 | Group 3 | Group 4 | Promoted Play-Off Winners | Relegated |
| 1999–2000 | Chênois | Wangen bei Olten | Locarno | Vaduz | Wangen bei Olten & Locarno | No Relegation |
| 2000–01 | Serrières | [FC FC Concordia Basel|Concordia Basel|Concordia] | Vaduz | — | Concordia & Vaduz | No Relegation |
| 2001–02 | Colombier | Schaffhausen | Malcantone Agno | — | Wohlen & Schaffhausen | No Relegation |
| 2002–03 | Meyrin | YF Juventus | Malcantone Agno | — | Bulle, Chiasso
Malcantone Agno & Meyrin | Rapperswil-Jona & Stade Nyonnais |
| 2003–04 | Étoile-Carouge | YF Juventus | Locarno | — | YF Juventus & Baulmes | FC Altstetten & Vevey Sports |
| 2004–05 | Lausanne-Sport | Biel-Bienne | Tuggen | — | Lausanne-Sport & Locarno | No Relegation |
| 2005–06 | Servette | Biel-Bienne | Tuggen | — | Delémont & Servette | No Relegation |
| 2006–07 | Étoile-Carouge | Basel U-21 | Red Star Zürich | — | Cham & Gossau | No Relegation |
| 2007–08 | Nyon | Basel U-21 | Baden | — | Biel-Bienne & Stade Nyonnais | FC Brugg & SC Zofingen |
| 2008–09 | Étoile-Carouge | Basel U-21 | Chiasso | — | Le Mont & Kriens | Red Star Zürich & FC La Tour/Le Pâquier |
| 2009–10 | Sion U-21 | YF Juventus | Chiasso | — | Chiasso & Delémont | SC Cham & FC Emmenbrücke |
| 2010–11 | Meyrin | Schötz | Brühl | — | Brühl & Étoile-Carouge | SC Bümpliz 78, CS Chênois, US Terre-Sainte, FC Laufen, SC Buochs & Zug 94 |
| 2011–12 | FC Sion II | BSC Old Boys | FC Tuggen | — | 11 promoted clubs | No Relegation |
| 2012–13 | FC Le Mont | FC Baden | SC Cham | — | FC Le Mont & FC Köniz | UGS Genève, ES FC Malley, SV Muttenz, SC Dornach, FC Kreuzlingen & CS Biaschesi |
| 2013–14 | SC Düdingen | Neuchâtel Xamax | USV Eschen/Mauren | — | Neuchâtel Xamax & FC Rapperswil-Jona | FC Bulle, SC Zofingen, FC Thun II, Chur 97 & SV Höngg |
| 2014–15 | FC Stade Lausanne-Ouchy | SC Cham | FC Wettswil-Bonstetten | — | SC Cham & SC Kriens | FC Meyrin, FC Monthey, Concordia Basel, FC Grenchen, FC Lugano II & AC Taverne |
| 2015–16 | FC Stade Lausanne-Ouchy | FC Münsingen | FC Baden | — | FC Bavois, FC La Chaux-de-Fonds & FC United Zürich | Signal FC Bernex-Confignon, US Terre-Sainte, FC Bern, FC Dietikon & FC Kosova |
| 2016–17 | Yverdon Sport FC | FC Luzern II | FC Gossau | — | Yverdon Sport FC & FC Stade Lausanne-Ouchy | FC La Sarraz-Eclépens, FC Wangen bei Olten, FC Muri, FC Seefeld & Locarno |
| 2017–18 | BSC Young Boys II | FC Solothurn | AC Bellinzona | — | AC Bellinzona & FC Münsingen | SC Guin, FC Portalban-Gletterens, FC Sursee, Kickers Luzern, FC Seuzach & FC Balzers |
| 2018–19 | Etoile Carouge FC | Black Stars | FC Baden | — | Etoile Carouge FC & Black Stars | FC Thun II, FC Fribourg, SC Zofingen, BSC Old Boys, FC Mendrisio & FC United Zürich |
| 2019–20 | FC Lausanne-Sport II | SR Delemont | FC Tuggen | — | No Promotion | No Relegation |
| 2020–21 | BSC Young Boys II | FC Biel-Bienne | FC Wettswil-Bonstetten | — | BSC Young Boys II & FC Biel-Bienne | FC Azzurri 90, Olympique de Genève FC, SV Muttenz, Gossau, Red Star Zürich & FC Dietikon |
| 2021–22 | BSC Young Boys II | FC Biel-Bienne | FC Tuggen | — | FC Baden, FC Bulle, FC Luzern II & St. Gallen II | Team Vaud, Lancy FC, Zug 94, SC Buochs, FC Thalwil & FC Balzers |
| 2022–23 | Servette FC II | SR Delémont | FC Paradiso | — | Servette FC II, SR Delémont, FC Paradiso & FC Lugano II | FC Concordia Lausanne, FC Martigny-Sports, FC Muri AG, SC Dornach, FC Uzwil & FC Weesen |
| 2023–24 | FC Grand-Saconnex | FC Schötz | FC Tuggen | — | Grand-Saconnex & Vevey-Sports | Pully Football, US Terre-Sainte, FC Emmenbrücke, FC Muri, FC Balzers & FC Gossau |
| 2024–25 | FC Lausanne-Sport II | Grasshopper Club II | Kreuzlingen | — | Lausanne-Sport II & Kreuzlingen | FC Köniz, FC Linth 04, FC Rotkreuz, FC Thun II, FC Uzwil, Yverdon-Sport II |
| 2025–26 | | | | — | | |