1-Methyl-2-iodo-LSD
1-Methyl-2-iodo-LSD is a serotonin receptor modulator of the lysergamide family related to lysergic acid diethylamide. It is the 1-methyl derivative of 2-iodo-LSD. Extensive metabolism of other 1-methylated lysergamides to their secondary amine derivatives, for instance methysergide conversion into methylergometrine, has been observed. The properties and effects of MIL in humans are unknown. However, a radiolabeled form of MIL, 1-methyl-2-iodo-LSD, as well as the analogue 1-ethyl-2-iodo-LSD, have been developed for use as presumably non-hallucinogenic agents in imaging of serotonin receptors. -MIL has much greater selectivity for serotonin 5-HT2 receptors over dopamine receptors compared to LSD. MIL and -MIL were first described in the scientific literature by Beth J. Hoffman and colleagues by 1985.