1-Benzyl-4-piperidone


1-Benzyl-4-piperidone, also called N-benzyl-4-piperidone, is a derivative of 4-piperidone.

Physical properties

1-Benzyl-4-piperidone is normally in liquid state with a yellow color. It also has a strong odor. Additionally, 1-benzyl-4-piperidone has a solubility of 12 g/L in water at room temperature.

Pharmaceutical chemistry usage

Like the related compound 4-piperidone, 1-benzyl-4-piperidone can be used in the synthesis of fentanyl. While using 1-benzyl-4-piperidone as the starting precursor initially yields benzylfentanyl, the resulting compound can be converted to fentanyl, according to Paul Jassen's works.

Regulations

As other drug precursors, 1-benzyl-4-piperidone is heavily regulated like its parent chemical. It is for example a compound on the DEA list and a Class A precursor under Canada's CDSA law.